| Pair Name | Camptothecin, Rapamycin | ||
| Phytochemical Name | Camptothecin (PubChem CID: 24360 ) | ||
| Anticancer drug Name | Rapamycin (PubChem CID: 5284616 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Camptothecin, Rapamycin | |||
| Disease Info | [ICD-11: 2C73] | Ovarian cancer | Investigative | |
| Biological Phenomena | Induction-->Autophagy | |||
| Gene Regulation | Up-regulation | Expression | ATG5 | hsa9474 |
| Up-regulation | Activity | CASP9 | hsa842 | |
| Up-regulation | Expression | MAP1LC3B | hsa81631 | |
| In Vitro Model | SK-OV-3 | Ovarian serous cystadenocarcinoma | Homo sapiens (Human) | CVCL_0532 |
| In Vivo Model | Cells suspended in PBS were subcutaneously injected into the right back of mice. | |||
| Result | Autophagy-induced intracellular signaling fractional nano-drug system for synergistic anti-tumor therapy | |||
| No. | Title | Href |
|---|---|---|
| 1 | Autophagy-induced intracellular signaling fractional nano-drug system for synergistic anti-tumor therapy. J Colloid Interface Sci. 2023 Sep;645:986-996. doi: 10.1016/j.jcis.2023.05.031. | Click |
